The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 17, 2020
Filed:
Apr. 06, 2017
Applicant:
Istituto Nazionale Tumori Irccs “fondazione G. Pascale”, Naples, IT;
Inventors:
Maria Vincenza Carriero, Naples, IT;
Gennaro Ciliberto, Rome, IT;
Katia Bifulco, Boscotrecase, IT;
Antonello Pessi, Rome, IT;
Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 5/107 (2006.01); C07K 5/10 (2006.01); C07K 5/09 (2006.01); A61P 35/00 (2006.01); A61K 51/08 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 5/1016 (2013.01); A61K 51/088 (2013.01); A61P 35/00 (2018.01); C07K 5/0817 (2013.01); C07K 5/1002 (2013.01); C07K 5/1027 (2013.01); A61K 38/00 (2013.01); Y02A 50/395 (2018.01);
Abstract
The present invention discloses retro-inverso peptides and pharmaceutical composition containing them. The peptides of the invention prevent key events occurring during the metastatic process, i.e. invasion of the extracellular matrix, formation of a capillary network, and the entry into bloodstream. They are therefore useful in the treatment of diseases and conditions that are sustained by an increase of cell motility, cell invasion, and/or angiogenesis, such as tumors and chronic inflammation.