The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10836786 B1

PDF
Full Text
Expired
Date of Patent:
Nov. 17, 2020

Filed:

Jul. 21, 2017
Applicant:

Jiangsu Hansoh Pharmaceutical Group Co., Ltd., Lianyungang, CN;

Inventors:

Xiang Li, Jiangsu, CN;

Jun Yu, Jiangsu, CN;

Haizhou Yu, Jiangsu, CN;

Jinjia Wang, Jiangsu, CN;

Lei He, Jiangsu, CN;

Zuyin Du, Jiangsu, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 7/04 (2006.01); C07H 15/04 (2006.01); C07H 1/00 (2006.01); C07D 309/10 (2006.01); A61P 3/10 (2006.01);
U.S. Cl.
CPC ...
C07H 7/04 (2013.01); A61P 3/10 (2018.01); C07D 309/10 (2013.01); C07H 1/00 (2013.01); C07H 15/04 (2013.01); C07B 2200/13 (2013.01);
Abstract

Disclosed are a crystal form of a dapagliflozin intermediate and a preparation method therefor, and specifically disclosed are a crystal form of the dapagliflozin intermediate (2S,3R,4S,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyOphenyl)-2-ethoxy-6-(methylhydroxyl) tetrahydro-2H-pyran-3,4,5-triol and a preparation method therefor. The advantages thereof lie in that an intermediate can be highly purified to obtain a sample with a purity of 99.3% or more, which has an important significance for improving the quality of the dapagliflozin, and the preparation process is simple and suitable for industrial production.


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