The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 17, 2020

Filed:

Jun. 12, 2019
Applicant:

Oriental(luzhou) Agrochemicals. Co., Ltd, Sichuan, CN;

Inventors:

Yinwei Sun, Sichuan, CN;

Zhongyuan Wang, Sichuan, CN;

Pan Zhang, Sichuan, CN;

Bangchi Chen, Sichuan, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 498/04 (2006.01); C07C 55/28 (2006.01); C07C 13/20 (2006.01); C07C 67/22 (2006.01); C07C 67/30 (2006.01); C07C 69/38 (2006.01); C07C 255/31 (2006.01); C07C 253/30 (2006.01); C07C 255/33 (2006.01); C07C 253/34 (2006.01); C07C 69/612 (2006.01); A01N 43/90 (2006.01);
U.S. Cl.
CPC ...
C07D 498/04 (2013.01); A01N 43/90 (2013.01); C07C 13/20 (2013.01); C07C 55/28 (2013.01); C07C 67/22 (2013.01); C07C 67/30 (2013.01); C07C 69/38 (2013.01); C07C 69/612 (2013.01); C07C 253/30 (2013.01); C07C 253/34 (2013.01); C07C 255/31 (2013.01); C07C 255/33 (2013.01);
Abstract

Disclosed are a method for preparing 2-(cyclohexenylidene) malonic acid derivatives and uses thereof. In this method, an olefin and a 2-substituted malonic acid derivative are used as starting materials to prepare the 2-(cyclohexenylidene) malonic acid derivative in the presence of a catalyst through cyclization reaction. This method has the following advantages: (1) the method can be very efficiently used for the synthesis of highly sterically-hindered 2-(2,6-disubstituted cyclohexenylidene) malonic acid derivatives; (2) the reaction yield is high, the reaction conditions are mild, and the wastes are less, favorable for industrial production. More importantly, the present invention extends the further use of 2-(cyclohexenylidene)malonic acid derivatives in organic synthesis, especially in the synthesis of 2-aryl malonic acid derivatives and their corresponding drugs such as Pinoxaden.


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