The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 17, 2020
Filed:
Nov. 27, 2017
Applicant:
North Carolina State University, Raleigh, NC (US);
Inventors:
Jonathan S. Lindsey, Raleigh, NC (US);
Shaofei Zhang, Raleigh, NC (US);
Assignee:
North Carolina State University, Raleigh, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/22 (2006.01); A61P 35/00 (2006.01); A61K 31/409 (2006.01);
U.S. Cl.
CPC ...
C07D 487/22 (2013.01); A61K 31/409 (2013.01); A61P 35/00 (2018.01);
Abstract
Described herein are bacteriochlorins comprising an annulated isocyclic ring such as a compound Formula I: or a metal conjugate thereof, wherein: R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, and Z are each as defined herein. Also described are methods and intermediates for the synthesis of bacteriochlorins comprising an annulated isocyclic ring, and methods of using such bacteriochlorins for, among other things, diagnostic and therapeutic purposes such as, e.g., luminescent compounds in flow cytometry, and/or as active agents in photodynamic therapy (PDT).