The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 17, 2020
Filed:
Jun. 21, 2017
The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);
The University of North Carolina AT Chapel Hill, Chapel Hill, NC (US);
Matthew Brian Boxer, New Market, MD (US);
Xiaodong Wang, Chapel Hill, NC (US);
Kyle Ryan Brimacombe, Bethesda, MD (US);
Mindy Irene Emily Davis, Rockville, MD (US);
Yuhong Fang, Rockville, MD (US);
Matthew Hall, Rockville, MD (US);
Ajit Jadhav, Chantilly, VA (US);
Surendra Karavadhi, Gaithersburg, MD (US);
Li Liu, Germantown, MD (US);
Natalia Martinez, Rockville, MD (US);
Andrew Louis McIver, Durham, NC (US);
Rajan Pragani, Gaithersburg, MD (US);
Jason Matthew Rohde, Poolesvile, MD (US);
Anton Simeonov, Bethesda, MD (US);
Wei Zhao, Rockville, MD (US);
Min Shen, Boyds, MD (US);
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, Chapel Hill, NC (US);
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, Bethesda, MD (US);
Abstract
A compound of Formula II or a pharmaceutically acceptable salt thereof, wherein CyN is a cyclic amine group bound via a nitrogen atom; X is C or N; Rand Rare each independently a halogen, CN, CF, CHF, CHF, a C-C10alkyl group, a C1-Calkoxy group, a di(C-Calkyl)amino; m and n are each independently 1, 2, or 3, and represents either a single bond or a double bond, wherein the racemic mixture of 3-(4-(4-chlorophenyl)thiazol-2-yl)-1-(2-ethyl-5-methoxyphenyl)-6-(2-methylprop-1-en-1-yl)-5-(piperazine-1-carbonyl)pyridin-2(1H)-one atropisomers is excluded.