The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 17, 2020

Filed:

Dec. 06, 2017
Applicant:

Sharp Life Science (Eu) Limited, Oxford, GB;

Inventors:
Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); B01L 7/00 (2006.01); G01N 27/447 (2006.01); G05D 23/19 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502792 (2013.01); B01L 3/50273 (2013.01); B01L 3/502707 (2013.01); B01L 3/502715 (2013.01); B01L 7/525 (2013.01); B01L 7/54 (2013.01); G01N 27/44704 (2013.01); G01N 27/44708 (2013.01); G01N 27/44791 (2013.01); G05D 23/19 (2013.01); B01L 3/50851 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/089 (2013.01); B01L 2300/0816 (2013.01); B01L 2300/0887 (2013.01); B01L 2300/18 (2013.01); B01L 2300/1805 (2013.01); B01L 2300/1822 (2013.01); B01L 2300/1827 (2013.01); B01L 2300/1861 (2013.01); B01L 2300/1894 (2013.01); B01L 2400/0427 (2013.01);
Abstract

An EWOD device for processing multiple droplets through multiple temperature zones. The device is configured to achieve a high spatial density of temperature zones with a wide temperature difference between hot and cold zones. A first set of temperature control elements is arranged above (or below) a fluid gap in an EWOD device and a second set of temperature control elements is arranged below (or above) the fluid gap. A temperature control element of one set is offset from temperature control elements of the other set in the plane of the fluid gap. The temperature control element of one set may be located at a different separation from the fluid gap to the temperature control element of the other set. The device has an optional temperature control element and/or arrangement which offsets the low temperature point from the inlet temperature. The two sets of temperature control elements are substantially interacting, in the sense that they cannot be considered to be thermally isolated from one another. This invention also describes methods to process multiple droplets within the multiple temperature zones.


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