The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 17, 2020

Filed:

Dec. 20, 2018
Applicant:

University of Massachusetts, Boston, MA (US);

Inventors:

Beth McCormick, Haverhill, MA (US);

Regino Mecado-Lubo, Worcester, MA (US);

Assignee:

University of Massachusetts, Boston, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/16 (2006.01); A61K 47/54 (2017.01); A61K 47/64 (2017.01); A61K 47/68 (2017.01); A61K 47/69 (2017.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 38/164 (2013.01); A61K 45/06 (2013.01); A61K 47/54 (2017.08); A61K 47/542 (2017.08); A61K 47/64 (2017.08); A61K 47/6811 (2017.08); A61K 47/6923 (2017.08); Y02A 50/481 (2018.01);
Abstract

The invention provides compositions and methods for reducing one or more symptoms of disease by administering compositions comprising SipA. The invention's compositions and methods are particularly advantageous in reducing symptoms of diseases that are associated with overexpression of P-gp and/or p53. The invention's compositions and methods are useful in reducing cancer symptom and/or cancer multidrug resistance (MDR). The invention provides a method for reducing one or more symptoms of cancer in a mammalian subject in need thereof, comprising administering to said subject a composition comprising purified SipA. In one embodiment, said SipA is operably conjugated to a nanoparticle. In another embodiment, said cancer comprises cancer cells resistant to at least one cytotoxin.


Find Patent Forward Citations

McCormick, Beth. (2020). Compositions and methods for treating disease usingt3ss effector protein (sipa) (U.S. Patent No. 10835575). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10835575

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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