The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 17, 2020

Filed:

May. 05, 2017
Applicants:

Shanghai Fochon Pharmaceutical Co., Ltd., Shanghai, CN;

Fochon Pharmaceuticals, Ltd., Nan'an District, Chongqing, CN;

Inventors:

Xingdong Zhao, Chongqing, CN;

Tongshuang Li, Surrey, CA;

Zhifang Chen, Chongqing, CN;

Rui Tan, Chongqing, CN;

Ling Chen, Chongqing, CN;

Xianlong Wang, Chongqing, CN;

Lijun Yang, Chongqing, CN;

Zuwen Zhou, Chongqing, CN;

Yanxin Liu, Chongqing, CN;

Min Lin, Chongqing, CN;

Jing Sun, Chongqing, CN;

Weibo Wang, Moraga, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); C07D 495/04 (2006.01); A61K 31/5377 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); C07D 495/04 (2013.01);
Abstract

Certain CDK4/6 inhibitors and pharmaceutically acceptable salts thereof are described. In particular, these compounds can inhibit kinase activity of CDK4/6 and may be useful for the treatment of hyper-proliferative diseases like cancer and inflammation. In addition, the pharmaceutical compositions thereof and methods of use thereof are also described.


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