The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 17, 2020

Filed:

Jan. 15, 2015
Applicant:

The Johns Hopkins University, Baltimore, MD (US);

Inventors:

Peter M. Abadir, Woodstock, MD (US);

Jeremy D. Walston, Baltimore, MD (US);

Assignee:

THE JOHNS HOPKINS UNIVERSITY, Baltimore, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4178 (2006.01); G01N 33/566 (2006.01); A61K 31/41 (2006.01); A61K 31/4184 (2006.01); C07K 14/705 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4178 (2013.01); A61K 9/0014 (2013.01); A61K 31/41 (2013.01); A61K 31/4184 (2013.01); C07K 14/705 (2013.01); G01N 33/566 (2013.01);
Abstract

Provided herein is a novel mitochondrial Angiotensin II type 1 and type 2 ATR and ATR receptor which plays a role in protection of mitochondria against oxidative damage. Evidence from animal studies indicates a role for this receptor in preservation of mitochondria and up-regulation of survival genes, anti-inflammatory action, and improvement of wound healing in the skin and soft tissues. Pharmaceutical compositions for treatment directed to preserving mitochondrial function, anti-inflammation, wound healing and decreasing the signs of aging, as well as medicaments and their use are also provided.


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