The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 10, 2020
Filed:
Sep. 22, 2011
Applicant:
Anders Ohrn, Vancouver, CA;
Inventor:
Anders Ohrn, Vancouver, CA;
Assignee:
ZYMEWORKS INC., Vancouver, CA;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/48 (2006.01); G16B 5/00 (2019.01); G01N 33/531 (2006.01); G01N 33/68 (2006.01); G16B 15/00 (2019.01); G06G 7/58 (2006.01);
U.S. Cl.
CPC ...
G16B 5/00 (2019.02); G01N 33/531 (2013.01); G01N 33/68 (2013.01); G16B 15/00 (2019.02); G01N 2500/00 (2013.01);
Abstract
The invention provides a computer implemented method of quantifying the quality of packing for a residue comprising one or more residue atoms in a first protein in a first conformation, the method comprising: (a) calculating one or more close contact potentials based on a distance between the one or more residue atoms and one or more environment atoms, (b) calculating a contact area of the one or more residue atoms that is exposed to the one or more environment atoms and (c) calculating a close contact surface density (CCSD) by dividing the sum of the one or more close contact potentials by the contact area.