The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 10, 2020

Filed:

Dec. 27, 2016
Applicant:

Celgene Corporation, Summit, NJ (US);

Inventors:

Brian E. Cathers, San Diego, CA (US);

Philip Chamberlain, San Diego, CA (US);

Antonia Lopez-Girona, San Diego, CA (US);

Gang Lu, San Diego, CA (US);

Assignee:

CELGENE CORPORATION, Summit, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); G01N 33/50 (2006.01); G16B 30/00 (2019.01); G01N 33/566 (2006.01); C07D 401/04 (2006.01); A61K 31/4035 (2006.01); C07K 14/47 (2006.01); C12N 15/62 (2006.01); G01N 33/573 (2006.01); A61K 38/18 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5008 (2013.01); A61K 31/4035 (2013.01); A61K 38/00 (2013.01); C07D 401/04 (2013.01); C07K 14/4702 (2013.01); C12N 15/62 (2013.01); G01N 33/566 (2013.01); G01N 33/573 (2013.01); G16B 30/00 (2019.02); A61K 38/18 (2013.01); C07K 2319/95 (2013.01); C12Y 203/02 (2013.01);
Abstract

Provided herein are compositions, therapeutic methods, screening methods, computational methods and biomarkers based upon the elucidation of the interaction among cereblon, its substrates and certain compounds or agents, including small molecules, peptides, and proteins.


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