The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 10, 2020

Filed:

Sep. 25, 2015
Applicant:

Northwestern University, Evanston, IL (US);

Inventors:

Ben Urban, Evanston, IL (US);

Hao F. Zhang, Deerfield, IL (US);

Cheng Sun, Wilmette, IL (US);

Biqin Dong, Evanston, IL (US);

Assignee:

Northwestern University, Evanston, IL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 21/64 (2006.01); G01J 1/42 (2006.01); G02B 21/36 (2006.01); G01N 21/65 (2006.01); G02B 21/00 (2006.01); G02B 27/58 (2006.01); G01N 21/84 (2006.01); G01N 33/483 (2006.01);
U.S. Cl.
CPC ...
G01J 1/4228 (2013.01); G01N 21/6458 (2013.01); G01N 21/65 (2013.01); G01N 21/84 (2013.01); G01N 33/483 (2013.01); G02B 21/008 (2013.01); G02B 21/0032 (2013.01); G02B 21/0064 (2013.01); G02B 21/0076 (2013.01); G02B 21/367 (2013.01); G02B 27/58 (2013.01);
Abstract

Certain examples disclose systems and methods for imaging a target. An example method includes: a) activating a subset of light-emitting molecules in a wide field area of a target using an excitation light; b) capturing one or more images of the light emitted from the subset of the molecules illuminated with the excitation light; c) localizing one or more activated light emitting molecules using one or more single molecule microscopic methods to obtain localization information; d) simultaneously capturing spectral information for the same localized activated light emitting molecules using one or more spectroscopic methods; e) resolving one or more non-diffraction limited images of the area of the target using a combination of the localization and spectral information for the localized activated light emitting molecules; and f) displaying the one or more non-diffraction limited images.


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