The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 10, 2020

Filed:

Jul. 17, 2019
Applicant:

The University of British Columbia, Vancouver, CA;

Inventors:

Andrea Marziali, North Vancouver, CA;

Joel Pel, Vancouver, CA;

Jason Donald Thompson, Vancouver, CA;

Gosuke Shibahara, Vancouver, CA;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12Q 1/6806 (2018.01); G01N 33/53 (2006.01); G01N 33/543 (2006.01); G01N 33/574 (2006.01); G01N 33/68 (2006.01); C12N 15/10 (2006.01); B03C 7/02 (2006.01); C12Q 1/6837 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6806 (2013.01); B03C 7/023 (2013.01); C12N 15/101 (2013.01); C12N 15/1003 (2013.01); C12Q 1/6837 (2013.01); G01N 33/5308 (2013.01); G01N 33/543 (2013.01); G01N 33/574 (2013.01); G01N 33/689 (2013.01); G01N 2800/385 (2013.01);
Abstract

Methods and apparatus for separating, concentrating and/or detecting molecules based on differences in binding affinity to a probe are provided. The molecules may be differentially modified. The molecules may be differentially methylated nucleic acids. The methods can be used in fields such as epigenetics or oncology to selectively concentrate or detect the presence of specific biomolecules or differentially modified biomolecules, to provide diagnostics for disorders such as fetal genetic disorders, to detect biomarkers in cancer, organ failure, disease states, infection or the like.


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