The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 10, 2020
Filed:
Sep. 20, 2017
Roche Sequencing Solutions, Inc., Pleasanton, CA (US);
Roche Molecular Systems, Inc., Pleasanton, CA (US);
Aruna Ayer, Sunnyvale, CA (US);
Cleoma Arnold, San Jose, CA (US);
Charles Schwab, Santa Clara, CA (US);
Preethi Sarvabhowman, Santa Clara, CA (US);
Eileen Thai, San Jose, CA (US);
Ilya Lederman, San Francisco, CA (US);
Colin McGaw, Santa Clara, CA (US);
Evan Amato, Menlo Park, CA (US);
Barbara Eckert, El Cerrito, CA (US);
Shawn Suko, Alameda, CA (US);
Mara Boenitz-Dulat, Tutzing, DE;
Bigna Woersdoerfer, Munich, DE;
David Wunderlich, Penzberg, DE;
Roche Sequencing Solutions, Inc., Pleasanton, CA (US);
Roche Molecular Systems, Inc., Pleasanton, CA (US);
Abstract
The present disclosure provides variant Pol6 polymerase polypeptides, compositions comprising the Pol6 variant polypeptides, and methods for using the variant Pol6 polypeptides for determining the sequencing of nucleic acids, for example, by nanopore sequencing. The variant Pol6 polymerases possess decreased rates of dissociation of template from the polymerase-template complex, which result in increased processivity relative to the parental Pol6 polypeptides from which they are derived.