The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 10, 2020

Filed:

Dec. 01, 2016
Applicant:

Ucb Biopharma Sprl, Brussels, BE;

Inventor:
Assignee:

UCB BIOPHARMA SRL, Brussels, BE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/39 (2006.01); C07K 16/00 (2006.01); G01N 33/68 (2006.01); C07K 16/14 (2006.01); C07K 16/46 (2006.01);
U.S. Cl.
CPC ...
C07K 16/468 (2013.01); C07K 14/39 (2013.01); C07K 16/00 (2013.01); C07K 16/14 (2013.01); G01N 33/6854 (2013.01); C07K 2319/00 (2013.01);
Abstract

The present invention relates to a method of identifying, separating and characterizing a cell or a population of cells, by capturing at the cell surface, secreted soluble substances (such as an immunoglobulin) that cell or population of cell secrete. This is achieved by combing on a heterodimerically-tethered multispecific protein complex combining a binding specificity for the secreted molecule and a binding specificity for a surface antigen specific for that cell or population of cells. This method may be used in research and experimental purposes, such as patients' stratification in preparation of clinical trials or personalized therapies by identifying cell populations relevant to a pathology and/or prognosis.


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