The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 10, 2020
Filed:
Apr. 20, 2015
Applicant:
Consejo Superior DE Investigaciones Científicas, Madrid, ES;
Inventors:
José Ignacio Casal Álvarez, Madrid, ES;
Rubén Álvaro Bartolome Conde, Madrid, ES;
Assignee:
CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS, Madrid, ES;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/30 (2006.01); A61P 35/00 (2006.01); C12N 15/62 (2006.01); C07K 16/28 (2006.01); G01N 33/574 (2006.01); C12N 5/12 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2896 (2013.01); A61P 35/00 (2018.01); C07K 16/30 (2013.01); C12N 5/12 (2013.01); C12N 15/62 (2013.01); G01N 33/57484 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/55 (2013.01); C07K 2317/56 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C12N 2015/8518 (2013.01); G01N 33/57438 (2013.01); G01N 33/57446 (2013.01);
Abstract
The disclosure relates to agents binding specifically to human cadherin 17 (CDH17), and/or to human cadherin 5 (CDH5), and/or to human cadherin 6 (CDH6), and/or to human cadherin 20 (CDH20). The disclosure also relates to the use of these agents in therapy, methods for diagnosis and/or prognosis and/or stratification of a cancer in a subject, and pharmaceutical compositions comprising said agents. The disclosure also relates to cancer markers and markers of metastasis.