The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 10, 2020
Filed:
Apr. 29, 2016
Applicant:
Medimmune Limited, Cambridge, GB;
Inventors:
Tristan Vaughan, Cambridge, GB;
David Lowe, Cambridge, GB;
Stacey Chin, Cambridge, GB;
Benjamin David Grimshaw, Cambridge, GB;
James Button, Cambridge, GB;
Assignee:
Medimmune Limited, Cambridge, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C40B 40/10 (2006.01); C07K 16/00 (2006.01); C07K 16/24 (2006.01); C07K 16/26 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C07K 16/005 (2013.01); C07K 16/24 (2013.01); C07K 16/26 (2013.01); C07K 16/28 (2013.01); C07K 2317/21 (2013.01); C07K 2317/33 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/567 (2013.01); C07K 2317/622 (2013.01); C07K 2317/76 (2013.01); C07K 2317/90 (2013.01); C40B 40/10 (2013.01);
Abstract
The present invention relates to a library (in particular a phage display library) from which an improved human antibody having greater specificity and potency for its target may be generated; and to methods of generating such a human antibody. In particular, the invention relates to a human antibodies against challenging targets obtainable from such a library and which have HCDR3s of at least 18 amino acids in length.