The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 10, 2020
Filed:
Oct. 24, 2017
Applicant:
Loyola University of Chicago, Maywood, IL (US);
Inventors:
I. Caroline Le Poole, Downers Grove, IL (US);
Jose Alejandro Guevara, Chicago, IL (US);
Andrew Zloza, Chicago, IL (US);
Assignee:
LOYOLA UNIVERSITY OF CHICAGO, Chicago, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/008 (2006.01); C07K 14/47 (2006.01); A01K 67/027 (2006.01); A61K 38/08 (2019.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4705 (2013.01); A01K 67/0276 (2013.01); A61K 38/08 (2013.01); C07K 14/47 (2013.01); A01K 2217/075 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0325 (2013.01); A61K 48/005 (2013.01);
Abstract
Methods of treating autoimmune diseases, such as vitiligo, by using compositions comprising DNA encoding a variant inducible heat shock protein 70 (HSP70i) having a mutation in the dendritic cell binding region thereof (HSP70i435-447) or an isolated variant gene product in the form of HSP70i with a modification in the dendritic cell activating region thereof (HSP70i435-447).