The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 10, 2020

Filed:

Nov. 04, 2019
Applicants:

Onl Therapeutics, Inc., Ann Arbor, MI (US);

The Regents of the University of Michigan, Ann Arbor, MI (US);

Inventors:

Cagri G. Besirli, Ann Arbor, MI (US);

Alexander J. Bridges, Saline, MI (US);

John K. Freshley, Ann Arbor, MI (US);

William A. Hunke, Middletown, DE (US);

Linda L. Johnson, Ann Arbor, MI (US);

Francis X. Smith, Salem, NH (US);

Ethan Sylvain, Manchester, NH (US);

David N. Zacks, Ann Arbor, MI (US);

Assignees:

ONL THERAPEUTICS. INC., Ann Arbor, MI (US);

THE REGENT OF THE UNIVERSITY OF MICHIGAN, Ann Arbor, MI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 7/08 (2006.01); C07K 14/71 (2006.01); A61P 27/02 (2006.01);
U.S. Cl.
CPC ...
C07K 7/08 (2013.01); A61P 27/02 (2018.01); C07K 14/71 (2013.01); A61K 38/00 (2013.01); Y02A 50/401 (2018.01); Y02A 50/423 (2018.01);
Abstract

Provided herein are compositions including peptides, pharmaceutical preparations thereof, and methods of preventing photoreceptor death therewith and protecting of retinal cells, including, but not limited to, photoreceptors and retinal pigment epithelium, from Fas- or TRAIL-mediated apoptosis.


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