The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 10, 2020

Filed:

Jun. 20, 2019
Applicant:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Inventors:

Thomas H. Graham, Quincy, MA (US);

Tao Yu, Edison, NJ (US);

Yonglian Zhang, Metuchen, NJ (US);

John A. McCauley, Maple Glen, PA (US);

Assignee:

MERCK SHARP & DOHME CORP., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4985 (2006.01); C07D 498/22 (2006.01); A61P 31/18 (2006.01); C07D 498/16 (2006.01); A61K 31/407 (2006.01); A61K 31/4188 (2006.01); A61K 31/5365 (2006.01); A61K 31/553 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C07D 498/22 (2013.01); A61K 31/407 (2013.01); A61K 31/4188 (2013.01); A61K 31/4985 (2013.01); A61K 31/5365 (2013.01); A61K 31/553 (2013.01); A61P 31/18 (2018.01); C07D 498/16 (2013.01); A61K 2300/00 (2013.01); C12N 15/1132 (2013.01);
Abstract

The present invention relates to Tetracyclic Heterocycle Compounds of Formula and pharmaceutically acceptable salts or prodrug thereof, wherein A, X, R, R, Rand Rare as defined herein. The present invention also relates to compositions comprising at least one Tetracyclic Heterocycle Compound, and methods of using the Tetracyclic Heterocycle Compounds for treating or preventing HIV infection in a subject.


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