The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 10, 2020

Filed:

Dec. 01, 2016
Applicant:

Zhejiang Jianfeng-yien Biotechnology Co., Ltd., Jinhua, CN;

Inventors:

Haixiao Zhai, Bedford, MA (US);

Fan Wu, Brookline, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 495/04 (2006.01); A61P 37/02 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 495/04 (2013.01); A61P 35/00 (2018.01); A61P 37/02 (2018.01);
Abstract

Compounds having the general formula I or III, ad pharmaceutical compositions comprising the same. The compounds of the present invention are useful as selective mutant epidermal growth factor receptor tyrosine kinase (EGFR-TK) inhibitor, and for the treatment of EGFR related diseases and disorders such as cancer.


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