The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 10, 2020
Filed:
Jun. 01, 2017
Galapagos NV, Mechelen, BE;
Frédéric Gilbert Labéguère, Frouzins, FR;
Rama Heng, Paris, FR;
Frédéric André De Ceuninck, Paris, FR;
Luke Jonathan Alvey, Romainville, FR;
David Amantini, Romainville, FR;
Franck Laurent Brebion, Romainville, FR;
Pierre Marc Marie Joseph Deprez, Romainville, FR;
Romain Luc Marie Gosmini, Romainville, FR;
Hélène Marie Jary, Romainville, FR;
Christophe Peixoto, Romainville, FR;
Iuliana Ecaterina Pop-Botez, Houilles, FR;
Marie Laurence Claire Varin, Romainville, FR;
GALAPAGOS NV, Mechelen, BE;
Abstract
The present invention discloses compounds according to Formula I: Wherein R, R, R, R, R, R, the subscript n and Cy are as defined herein. The present invention relates to compounds inhibiting ADAMTS, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of inflammatory diseases, and/or diseases involving degradation of cartilage and/or disruption of cartilage homeostasis by administering the compound of the invention.