The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 10, 2020
Filed:
Mar. 30, 2018
Applicant:
Global Blood Therapeutics, Inc., South San Francisco, CA (US);
Inventors:
Brian W. Metcalf, South San Francisco, CA (US);
Zhe Li, San Diego, CA (US);
Qing Xu, South San Francisco, CA (US);
Stephen L. Gwaltney, II, South San Francisco, CA (US);
Jason R. Harris, South San Francisco, CA (US);
Calvin W. Yee, South San Francisco, CA (US);
Assignee:
Global Blood Therapeutics, Inc., South San Francisco, CA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 401/04 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); A61K 31/445 (2006.01); A61K 31/5375 (2006.01); C07D 401/12 (2006.01); C07D 471/04 (2006.01); C07D 257/04 (2006.01); C07D 213/30 (2006.01); C07D 487/04 (2006.01); C07D 231/56 (2006.01); C07D 211/62 (2006.01); C07D 213/64 (2006.01); C07C 65/30 (2006.01); C07F 7/08 (2006.01); A61K 8/49 (2006.01); C07D 211/70 (2006.01); C07D 213/69 (2006.01); C07D 227/08 (2006.01); C07D 405/04 (2006.01);
U.S. Cl.
CPC ...
C07D 401/04 (2013.01); A61K 8/4913 (2013.01); A61K 31/445 (2013.01); A61K 31/5375 (2013.01); C07C 65/30 (2013.01); C07D 211/62 (2013.01); C07D 211/70 (2013.01); C07D 213/30 (2013.01); C07D 213/64 (2013.01); C07D 213/69 (2013.01); C07D 227/08 (2013.01); C07D 231/56 (2013.01); C07D 257/04 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 405/04 (2013.01); C07D 405/14 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07F 7/0812 (2013.01);
Abstract
Provide herein are compounds and pharmaceutical compositions suitable as modulators of hemoglobin, methods and intermediates for their preparation, and methods for their use in treating disorders mediated by hemoglobin and disorders that would benefit from tissue and/or cellular oxygenation.