The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 10, 2020
Filed:
Nov. 12, 2018
Applicant:
Wisconsin Alumni Research Foundation, Madison, WI (US);
Inventors:
Bianca R. Tomasini-Johansson, Madison, WI (US);
Glen S. Kwon, Madison, WI (US);
Pawel Waldemar Zbyszynski, Chicago, IL (US);
Nathan Sandbo, Middleton, WI (US);
Ksenija Bernau, Madison, WI (US);
Assignee:
WISCONSIN ALUMNI RESEARCH FOUNDATION, Madison, WI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/60 (2017.01); A61P 43/00 (2006.01); A61P 13/12 (2006.01); A61K 9/00 (2006.01); A61K 38/16 (2006.01); A61K 45/06 (2006.01); A61K 49/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/60 (2017.08); A61K 9/0019 (2013.01); A61K 9/0029 (2013.01); A61K 38/164 (2013.01); A61K 45/06 (2013.01); A61K 49/0056 (2013.01); A61P 13/12 (2018.01); A61P 43/00 (2018.01);
Abstract
Described herein is a mono-end PEGyated functional upstream domain (FUD), pharmaceutical compositions, and its use to inhibit fibrosis such as organ fibrosis, idiopathic pulmonary fibrosis and fibrosis associated with cancer. Also included are methods of probing for injured or repairing tissue in an individual in need thereof using the mono-end PEGyated-FUD.