The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 10, 2020
Filed:
Feb. 07, 2018
Applicant:
Indiana University Research and Technology Corporation, Indianapolis, IN (US);
Inventors:
Mervin C. Yoder, Indianapolis, IN (US);
Paul Critser, Indianapolis, IN (US);
Sherry Voytik-Harbin, Zionsville, IN (US);
Assignee:
Indiana University Research and Technology Corporation, Indianapolis, IN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/51 (2015.01); A61K 9/70 (2006.01); A61L 27/24 (2006.01); A61L 27/38 (2006.01);
U.S. Cl.
CPC ...
A61K 35/51 (2013.01); A61K 9/70 (2013.01); A61L 27/24 (2013.01); A61L 27/3808 (2013.01);
Abstract
Materials and methods are disclosed for controlling vasculogenesis using building blocks of a collagen matrix and endothelial colony forming cells (ECFC). The building blocks may be isolated by fractionating an acid soluble Type I collagen. The building blocks comprising monomers and/or oligomers may be recombined in desired ratios to alter the matrix microenvironment and to influence ECFC behavior.