The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 10, 2020
Filed:
Jun. 06, 2017
Applicant:
Fujifilm Cellular Dynamics, Inc., Madison, WI (US);
Inventors:
Matt George, Madison, WI (US);
Carrie Chavez, Madison, WI (US);
Chris McMahon, Madison, WI (US);
Wen Bo Wang, Madison, WI (US);
Lucas Chase, Madison, WI (US);
Brad Swanson, Madison, WI (US);
Assignee:
FUJIFILM Cellular Dynamics, Inc., Madison, WI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/30 (2015.01); B65D 25/20 (2006.01); G01N 33/50 (2006.01); C12N 9/02 (2006.01); C12Q 1/68 (2018.01); A61J 1/00 (2006.01); C12N 5/0793 (2010.01); C12Q 1/6876 (2018.01);
U.S. Cl.
CPC ...
A61K 35/30 (2013.01); A61J 1/00 (2013.01); B65D 25/205 (2013.01); C12N 5/0619 (2013.01); C12N 9/0071 (2013.01); C12Q 1/6876 (2013.01); G01N 33/5058 (2013.01); C12N 2501/15 (2013.01); C12N 2501/155 (2013.01); C12N 2501/41 (2013.01); C12N 2501/415 (2013.01); C12N 2501/727 (2013.01); C12N 2506/45 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/158 (2013.01); C12Y 114/16002 (2013.01); G01N 2333/4706 (2013.01);
Abstract
Methods are provided for efficient production of midbrain dopaminergic (DA) neurons. In some aspects, methods involve differentiation and selection of DA neurons for a transgenic pluripotent cell population (e.g., cells comprising a selectable marker gene). Cell populations produced by the instant methods and methods of their use are likewise provided.