The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 10, 2020
Filed:
Oct. 08, 2019
Applicant:
Principia Biopharma Inc., South San Francisco, CA (US);
Inventors:
Mohammad Reza Masjedizadeh, San Jose, CA (US);
Steven Gourlay, San Francisco, CA (US);
Assignee:
Principia Biopharma Inc., South San Francisco, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61P 25/00 (2006.01); A61K 31/5395 (2006.01); A61K 45/06 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61K 31/5395 (2013.01); A61K 45/06 (2013.01); A61P 25/00 (2018.01); C07D 487/04 (2013.01);
Abstract
Disclosed herein are processes for preparing 2-[(3R)-3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile free base (compound (I)), salts of compound (I) and solid state form of said salts. Also disclosed herein are pharmaceutical compositions comprising such salts and solid state form thereof and methods of treating cancer, autoimmune, and inflammatory diseases using compound (I) or a pharmaceutically acceptable salt thereof.