The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 10, 2020

Filed:

Dec. 26, 2018
Applicant:

Virginia Tech Intellectual Properties, Inc., Blacksburg, VA (US);

Inventors:

Rafael V. Davalos, Blacksburg, VA (US);

John H. Rossmeisl, Blacksburg, VA (US);

Paulo A. Garcia, Blacksburg, VA (US);

Assignee:

Other;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61B 18/12 (2006.01); A61B 18/14 (2006.01); A61N 1/32 (2006.01); C12N 13/00 (2006.01); A61B 18/00 (2006.01); A61B 34/10 (2016.01); A61N 1/05 (2006.01);
U.S. Cl.
CPC ...
A61B 18/1206 (2013.01); A61B 18/14 (2013.01); A61B 18/1477 (2013.01); A61N 1/327 (2013.01); C12N 13/00 (2013.01); A61B 2018/00446 (2013.01); A61B 2018/00577 (2013.01); A61B 2018/00613 (2013.01); A61B 2034/104 (2016.02); A61N 1/05 (2013.01);
Abstract

Methods for treating tissue with irreversible electroporation and immunotherapy are described. The methods include placing a probe in tissue within a human body, wherein the probe has at least a first electrode, applying a plurality of electrical pulses through the first electrode and a second electrode, causing irreversible electroporation (IRE) of the tissue within a target ablation zone, and administering one or more exogenous agents into the tissue within the target ablation zone or to the human, thereby stimulating or otherwise modulating an immune system response within the body.


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