The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 10, 2020
Filed:
Mar. 10, 2015
H. Lee Moffitt Cancer Center and Research Institute, Inc., Tampa, FL (US);
University of South Florida, Tampa, FL (US);
Robert J. Gillies, Tampa, FL (US);
Robert A. Gatenby, Tampa, FL (US);
Natarajan Raghunand, Tampa, FL (US);
John Arrington, Tampa, FL (US);
Olya Stringfield, Tampa, FL (US);
Yoganand Balagurunathan, Tampa, FL (US);
Dmitry B. Goldgof, Lutz, FL (US);
Lawrence O. Hall, Tampa, FL (US);
H. LEE. MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC., Tampa, FL (US);
UNIVERSITY OF SOUTH FLORIDA, Tampa, FL (US);
Abstract
Virtually every cancer patient is imaged with CT, PET or MRI. Importantly, such imaging reveals that tumors are complex and heterogeneous, often containing multiple habitats within them. Disclosed herein are methods for analyzing these images to infer cellular and molecular structure in each of these habitats. The methods can involve spatially superimposing two or more radiological images of the tumor sufficient to define regional habitat variations in two or more ecological dynamics in the tumor, and comparing the habitat variations to one or more controls to predict the severity of the tumor.