The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 03, 2020

Filed:

Sep. 28, 2015
Applicants:

The Regents of the University of California, Oakland, CA (US);

Cedars-sinai Medical Center, Los Angeles, CA (US);

Inventors:

Hsian-Rong Tseng, Los Angeles, CA (US);

Jiaoti Huang, Los Angeles, CA (US);

Edwin M. Posadas, Los Angeles, CA (US);

Jiefu Chen, Los Angeles, CA (US);

Hao Ho, Los Angeles, CA (US);

Zunfu Ke, Los Angeles, CA (US);

Ker-Chau Li, Los Angeles, CA (US);

Yi-Tsung Lu, Los Angeles, CA (US);

Jake Lichterman, Los Angeles, CA (US);

Min Song, Los Angeles, CA (US);

Leland W. K. Chung, Los Angeles, CA (US);

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/574 (2006.01); G01N 15/14 (2006.01); G01N 33/569 (2006.01); G01N 15/10 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57434 (2013.01); G01N 15/10 (2013.01); G01N 15/1475 (2013.01); G01N 33/56966 (2013.01); G01N 33/57488 (2013.01); G01N 2015/1006 (2013.01); G01N 2015/1488 (2013.01); G01N 2015/1493 (2013.01); G01N 2015/1497 (2013.01); G01N 2800/56 (2013.01);
Abstract

A method, system and computer-readable medium for assessing a disease condition of a cancer of a subject, including: receiving a blood sample from the subject; isolating a plurality of circulating tumor cells (CTCs) from the blood sample; measuring at least one of cell or cell nucleus sizes of each of the plurality of CTCs; determining a measured CTC size distribution of the plurality of CTCs based on the measuring; comparing the measured CTC size distribution to a reference CTC size distribution using a computer; and assigning the disease condition of the cancer of the subject based on the comparing.


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