The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 03, 2020
Filed:
Jul. 02, 2017
Applicant:
James Gigrich, Lorton, VA (US);
Inventor:
James Gigrich, Lorton, VA (US);
Assignee:
Other;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6876 (2018.01); G01N 33/50 (2006.01); G16B 40/00 (2019.01); G16C 20/30 (2019.01); G16C 20/80 (2019.01); G16B 25/10 (2019.01);
U.S. Cl.
CPC ...
C12Q 1/6876 (2013.01); G01N 33/5014 (2013.01); G01N 33/5067 (2013.01); G16B 40/00 (2019.02); G16C 20/30 (2019.02); C12Q 2600/142 (2013.01); C12Q 2600/158 (2013.01); G16B 25/10 (2019.02); G16C 20/80 (2019.02);
Abstract
The invention relates to methods and systems for high-throughput toxicity screening of compounds using Mahalanobis Values, and in particular comparing a normal unexposed transcriptome Mahalanobis Value in an in-vitro hepatocyte microassay against a calculated transcriptome Mahalanobis Value of hepatocytes exposed to a target compound for varying time periods and in varying concentrations.