The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 03, 2020
Filed:
Mar. 28, 2013
Hiroshima University, Hiroshima, JP;
Yasuyuki Yokosaki, Hiroshima, JP;
Norihisa Nishimichi, Hiroshima, JP;
Hiroshima University, Hiroshima, JP;
Abstract
Novel and effective anti-fibrosis agents are obtained. An anti-fibrosis agent containing an antagonist for integrin αis used. In addition, used is an antagonist containing an anti-integrin αantibody that specifically binds to at least one amino acid in a cap subdomain of an integrin α8 chain and a periphery thereof. Also, used is an anti-fibrosis agent containing an anti-integrin αantibody that specifically binds to R120 of an integrin α8 chain and a periphery thereof or S132 and a periphery thereof. Note that the above antagonists may each be an anti-integrin αantibody capable of binding to any of integrins αderived from a human, mouse, and rat.