The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 03, 2020
Filed:
Mar. 25, 2010
Applicants:
Abraham Scaria, Framingham, MA (US);
Gary White, Marlborough, MA (US);
Inventors:
Abraham Scaria, Framingham, MA (US);
Gary White, Marlborough, MA (US);
Assignee:
GENZYME CORPORATION, Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 19/00 (2006.01); C07K 14/715 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/7155 (2013.01); A61K 38/00 (2013.01); C07K 2319/30 (2013.01); C12N 2750/14143 (2013.01);
Abstract
Fusion proteins including an IL-17 receptor with a multimerization domain, or an IL-23 receptor and a multimerization domain, and recombinant viral vectors encoding such fusions, are described. The fusion proteins and vectors encoding such fusions, alone or in combination, can be used in methods for modulating the IL-17 and IL-23 signaling pathways and for treating or preventing diseases mediated by interleukin-17 and interleukin-23, such as immune-related and inflammatory diseases.