The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 03, 2020

Filed:

Jan. 13, 2017
Applicant:

Novo Nordisk A/s, Bagsvaerd, DK;

Inventors:

Jianhe Chen, Beijing, CN;

Jesper F. Lau, Farum, DK;

Janos Tibor Kodra, Copenhagen, DK;

Birgit Wieczorek, Copenhagen, DK;

Lars Linderoth, Hilleroed, DK;

Henning Thoegersen, Farum, DK;

Salka Elboel Rasmussen, Vaerloese, DK;

Patrick William Garibay, Holte, DK;

Assignee:

Novo Nordisk A/S, Bagsvaerd, DK;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/485 (2006.01); A61K 38/17 (2006.01); C07K 14/705 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/485 (2013.01); A61K 38/177 (2013.01); C07K 14/705 (2013.01); A61K 38/00 (2013.01);
Abstract

The invention relates to compounds derived from the EGF(A) domain of LDL-R, in particular compounds comprising a peptide analogue of the wild-type EGF(A) (LDL-R(293-332)) sequence and at least one substituent comprising at least one fatty acid group. The invention also relates to a pharmaceutical composition thereof and use a medicament. The novel EGF(A) compounds of the invention are useful as treatment e.g. in the field of cholesterol lowering, dyslipidaemia and cardiovascular disease.


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