The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 03, 2020
Filed:
Sep. 30, 2019
Applicant:
St. Jude Children's Research Hospital, Memphis, TN (US);
Inventors:
Assignee:
St. Jude Children's Research Hospital, Memphis, TN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 11/02 (2006.01); A61K 38/12 (2006.01); A61K 31/407 (2006.01); A61K 38/14 (2006.01); A61K 45/06 (2006.01); C07D 498/14 (2006.01); C07D 498/22 (2006.01); C07K 7/06 (2006.01); A61K 9/00 (2006.01); A61K 47/02 (2006.01); A61K 9/20 (2006.01); A61K 38/15 (2006.01);
U.S. Cl.
CPC ...
C07K 11/02 (2013.01); A61K 9/0019 (2013.01); A61K 9/2018 (2013.01); A61K 31/407 (2013.01); A61K 38/12 (2013.01); A61K 38/14 (2013.01); A61K 38/15 (2013.01); A61K 45/06 (2013.01); A61K 47/02 (2013.01); C07D 498/14 (2013.01); C07D 498/22 (2013.01); C07K 7/06 (2013.01); Y02A 50/469 (2018.01); Y02A 50/471 (2018.01); Y02A 50/475 (2018.01); Y02A 50/481 (2018.01);
Abstract
In one aspect, the invention relates to substituted urea depsipeptide analogs, derivatives thereof, and related compounds, which are useful as activators the ClpP endopeptidease; synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating infectious disease using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.