The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 03, 2020

Filed:

Oct. 16, 2018
Applicant:

Ramot AT Tel-aviv University Ltd., Tel Aviv, IL;

Inventors:

Illana Gozes, Ramat-Hasharon, IL;

Saar Oz, Ramat-Hasheron, IL;

Jacqueline Woang Cheing Tiong, Vancouver, CA;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 5/10 (2006.01); C07K 14/47 (2006.01); C07K 5/103 (2006.01); C07K 7/06 (2006.01); G01N 33/569 (2006.01); A61K 38/00 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C07K 5/10 (2013.01); C07K 5/1013 (2013.01); C07K 7/06 (2013.01); C07K 14/4711 (2013.01); G01N 33/56966 (2013.01); A61K 38/00 (2013.01); G01N 33/5005 (2013.01); G01N 2500/04 (2013.01);
Abstract

This invention provides novel compounds and methods for promoting cell survival and/or plasticity, especially in neuronal cells, by targeting the microtubule End Binding (EB) proteins and other associated proteins (e.g., drebrin). Methods for identifying potential modulators of cell death/plasticity are also described.


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