The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 03, 2020
Filed:
Jul. 05, 2016
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Amjad Ali, Freehold, NJ (US);
Xianhai Huang, Warren, NJ (US);
Yeon-Hee Lim, San Mateo, CA (US);
Rongze Kuang, Green Brook, NJ (US);
Heping Wu, Edison, NJ (US);
Rajan Anand, Fanwood, NJ (US);
Younong Yu, East Brunswick, NJ (US);
Edward Metzger, Laurel, MD (US);
Michael Man-Chu Lo, Bedminster, NJ (US);
Pauline C. Ting, New Providence, NJ (US);
Andrew W. Stamford, Chatham, NJ (US);
Paul Tempest, Taipei, TW;
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
The present invention is directed to compounds of generic formula (I): or pharmaceutically acceptable salts thereof that are believed to be useful as an A-receptor antagonist. The invention is further directed to methods of treating a patient (preferably a human) for diseases or disorders in which the A-receptor is involved. The invention further involves use of the compounds as an A-receptor antagonist and/or inhibitor for the preparation of a medicament for the treatment and/or prevention of diseases associated with inhibiting the receptor, which includes central nervous system disorders such as Parkinson's disease. The invention is also directed to pharmaceutical compositions which include an effective amount of a compound of formula (I), or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, and the use of the compounds and pharmaceutical compositions of the invention in the treatment of such diseases.