The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 03, 2020
Filed:
Mar. 30, 2016
Rigel Pharmaceuticals, Inc., South San Francisco, CA (US);
Marina Gelman, San Francisco, CA (US);
Todd Kinsella, Redwood City, CA (US);
Somasekhar Bhamidipati, Foster City, CA (US);
Ihab Darwish, San Carlos, CA (US);
Rajinder Singh, Belmont, CA (US);
Jiaxin Yu, San Carlos, CA (US);
Rigel Pharmaceuticals, Inc., South San Francisco, CA (US);
Abstract
Disclosed are pyrazole compounds, as well as pharmaceutical compositions and methods of use thereof. One embodiment is a compound having the structure and pharmaceutically acceptable salts, prodrugs and N-oxides thereof (and solvates and hydrates thereof), wherein A, X, Z, m, p, and Rare as described herein. In certain embodiments, a compound disclosed herein inhibits the activity of one or more members of the TGF-β superfamily, and can be used to treat disease by blocking such activity.