The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 03, 2020

Filed:

Mar. 24, 2015
Applicant:

The Trustees of Columbia University IN the City of New York, New York, NY (US);

Inventors:

Anil K. Lalwani, New York, NY (US);

Jeffrey W. Kysar, New York, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61M 5/00 (2006.01); A61M 37/00 (2006.01);
U.S. Cl.
CPC ...
A61M 37/0015 (2013.01); A61M 2037/003 (2013.01); A61M 2037/0023 (2013.01); A61M 2037/0046 (2013.01); A61M 2037/0053 (2013.01); A61M 2037/0061 (2013.01);
Abstract

The disclosed subject matter relates to a system and method for delivery of therapeutic agent to the inner ear. The system includes a plurality of micro-needles which can be delivered to the round window membrane by a delivery device, e.g. catheter, and is capable of controlled penetration of the round window membrane to create temporary and self-closing perforations. In some embodiments the micro-needles are hollow with a lumen for local drug delivery into the perforations. In other embodiments the micro-needles are solid and include a coating of therapeutic agent on exterior surface for delivery into the perforations.


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