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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10821130 B1

PDFFull Text
Date of Patent:
Nov. 03, 2020

Filed:

Sep. 29, 2017

Omega 3 fatty acids, no releasing compound and vitamin b12 as neuroprotectant in patients with no dementia

Applicant:

Nestec S.a., Vevey, CH;

Inventors:

Yvonne Beata Silber, Essertes, CH;

Jeroen Antonius Johannes Schmitt, Moudon, CH;

Corina Boschat, Lausanne, CH;

Julie Hudry-Labbe, Epalinges, CH;

Claus Rieker, St-Sulpice, CH;

Assignee:

Societe des Produits Nestle S.A., Vevey, CH;

Attorney:

K&L Gates LLP

Primary Examiner:

Kyung S Chang

Int. Cl.
CPC ...
A61K 31/714 (2006.01); A61K 31/202 (2006.01); A61K 31/4415 (2006.01); A61K 31/519 (2006.01); A61K 31/198 (2006.01); A61P 43/00 (2006.01); A61P 25/28 (2006.01); A61K 31/14 (2006.01); A61K 31/17 (2006.01); A61K 31/375 (2006.01); A61K 31/4406 (2006.01); A61K 33/00 (2006.01); A61K 31/197 (2006.01); A61K 31/341 (2006.01); A61K 31/355 (2006.01); A61K 31/4188 (2006.01); A61K 31/455 (2006.01); A61K 31/51 (2006.01); A61K 31/525 (2006.01); A61K 31/59 (2006.01); A61K 31/675 (2006.01); A61K 33/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/714 (2013.01); A61K 31/14 (2013.01); A61K 31/17 (2013.01); A61K 31/197 (2013.01); A61K 31/198 (2013.01); A61K 31/202 (2013.01); A61K 31/341 (2013.01); A61K 31/355 (2013.01); A61K 31/375 (2013.01); A61K 31/4188 (2013.01); A61K 31/4406 (2013.01); A61K 31/4415 (2013.01); A61K 31/455 (2013.01); A61K 31/51 (2013.01); A61K 31/519 (2013.01); A61K 31/525 (2013.01); A61K 31/59 (2013.01); A61K 31/675 (2013.01); A61K 33/00 (2013.01); A61K 33/04 (2013.01);
Abstract

A method of attenuating, treating or preventing cognitive aging in an individual who does not have dementia includes administering to the individual a therapeutically effective amount of a composition containing an omega-3 fatty acid, a nitric oxide releasing compound, and Vitamin B12. The composition is administered in a daily dose that provides 50 to 500 times the recommended daily requirement (RDA) of Vitamin B12 per day, for example about 200 times the RDA of Vitamin B12 per day. Optionally Vitamin B6 and/or Vitamin B9 can be included in the composition. The method can achieve a benefit that is one or more of decreasing brain atrophy, increasing or maintaining number of synapses, increasing amyloid-β phagocytosis, or decreasing or maintaining neuroinflammation in the non-demented individual. The method can prevent dementia in an individual at risk thereof, for example an elderly human.

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