The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 03, 2020

Filed:

Jun. 09, 2017
Applicant:

N.v. Nutricia, Zoetermeer, NL;

Inventors:

Sofia Lopes Da Silva, Groningen, NL;

Ladislaus Maria Broersen, Utrecht, NL;

Robert Johan Joseph Hageman, Utrecht, NL;

Jan Maarten Verkuijl, Utrecht, NL;

Assignee:

N.V. Nutricia, Zoetermeer, NL;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/593 (2006.01); A61K 31/07 (2006.01); A61K 31/202 (2006.01); A61K 31/4415 (2006.01); A61K 31/714 (2006.01); A61K 31/519 (2006.01); A61P 29/00 (2006.01); A61K 31/14 (2006.01); A61K 31/355 (2006.01); A61K 31/375 (2006.01);
U.S. Cl.
CPC ...
A61K 31/593 (2013.01); A61K 31/07 (2013.01); A61K 31/202 (2013.01); A61K 31/4415 (2013.01); A61K 31/519 (2013.01); A61K 31/714 (2013.01); A61P 29/00 (2018.01); A61K 31/14 (2013.01); A61K 31/355 (2013.01); A61K 31/375 (2013.01);
Abstract

The invention pertains to the use of therapeutically effective amounts of (i) vitamin A and/or functional equivalents, (ii) vitamin D and/or functional equivalents, and (iii) at least one omega-3 PUFA, preferably DHA and/or EPA, more preferably DHA and EPA, for the manufacture of a composition or medicament for treating, reducing and/or preventing neuroinflammation and/or symptoms associated with neuroinflammation in a subject in need thereof, as well as for reducing microglia activation, and/or for treating, reducing and/or preventing symptoms associated with excessive activation of microglia; and/or for reducing the secretion of inflammatory cytokines, preferably IL-6, and/or for treating, reducing and/or preventing symptoms associated with excessive secretion of inflammatory cytokines, in a subject in need thereof.


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