The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 03, 2020
Filed:
Mar. 15, 2017
Applicant:
Dicerna Pharmaceuticals, Inc., Lexington, MA (US);
Inventors:
Marc Abrams, Natick, MA (US);
Shanthi Ganesh, Shrewsbury, MA (US);
Assignee:
Dicerna Pharmaceuticals, Inc., Lexington, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61K 31/7088 (2006.01); A61K 9/00 (2006.01); A61P 35/00 (2006.01); A61K 9/51 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61K 9/0019 (2013.01); A61K 9/5123 (2013.01); A61K 31/7088 (2013.01); A61P 35/00 (2018.01); C12N 15/113 (2013.01); C12N 2310/14 (2013.01);
Abstract
Disclosed herein are methods for the treatment of cancer, comprising administering to a subject a β-catenin nucleic acid inhibitor molecule and a therapeutically effective amount of an MEK inhibitor or a c-Myc nucleic acid inhibitor molecule. Also disclosed herein is a pharmaceutical composition comprising a therapeutically effective amount of a β-catenin nucleic acid inhibitor molecule; a therapeutically effective amount of an MEK inhibitor or a c-Myc nucleic acid inhibitor molecule and at least one pharmaceutical carrier.