The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 03, 2020

Filed:

Jun. 29, 2016
Applicant:

University Industry Foundation, Yonsei University Wonju Campus, Wonju-si, Gangwon-do, KR;

Inventors:

Inho Choi, Wonju-si, KR;

Kyoungsook Park, Seoul, KR;

Hyun Woo Ju, Seoul, KR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/00 (2006.01); G01N 33/53 (2006.01); A61K 31/135 (2006.01); A61K 31/7076 (2006.01); A61K 33/04 (2006.01); A61P 21/00 (2006.01); C12N 15/01 (2006.01); G01N 33/50 (2006.01); A61K 38/08 (2019.01);
U.S. Cl.
CPC ...
A61K 31/135 (2013.01); A61K 31/7076 (2013.01); A61K 33/04 (2013.01); A61K 38/08 (2013.01); A61P 21/00 (2018.01); C12N 15/01 (2013.01); G01N 33/5061 (2013.01);
Abstract

The present invention relates to: a muscular atrophy-inducing agent containing, as an active ingredient, a hypometabolism-inducing substance selected from the group consisting of 3-iodothyronamine (T1AM), [D-Ala2,D-Leu5] enkephalin (DADLE), 5'-adenosine monophosphate (5′-AMP), and hydrogen sulfide (HS); a method for preparing a muscular atrophy study model comprising inducing muscular atrophy by administering the muscular atrophy-inducing agent; a study model prepared by the method; a screening method for a drug for preventing or treating muscular atrophy using the same; a composition for preventing or treating muscular hypertrophy; and a composition for facial muscle shrinkage. The muscular atrophy study model according to the present invention can provide a study model for an economic muscular atrophy study by using a hypometabolism-inducing substance which can be mass-produced, has an effect which may be usefully used by verification for screening of a drug for preventing or treating muscular atrophy, and can be usefully used as a compositions for preventing or treating muscular hypertrophy and a composition for facial muscle shrinkage through the muscular atrophy effect.


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