The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 03, 2020

Filed:

Oct. 02, 2014
Applicants:

The Board of Trustees of the University of Illinois, Urbana, IL (US);

Washington University IN St. Louis, St. Louis, MO (US);

Inventors:

John A. Rogers, Champaign, IL (US);

Igor Efimov, Wildwood, MO (US);

Sarah Gutbrod, St. Louis, MO (US);

Lizhi Xu, Urbana, IL (US);

Andrew Bonifas, Woodbury, MN (US);

Richard Chad Webb, Urbana, IL (US);

Ahyeon Koh, Champaign, IL (US);

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); A61B 5/03 (2006.01); A61B 5/11 (2006.01); A61H 23/02 (2006.01); A61B 5/145 (2006.01); A61B 5/0205 (2006.01); A61B 5/042 (2006.01); A61N 2/00 (2006.01); A61B 5/1473 (2006.01); A61N 1/05 (2006.01); A61B 18/14 (2006.01); A61N 5/06 (2006.01); A61N 1/375 (2006.01); A61N 1/362 (2006.01); A61B 18/00 (2006.01); A61B 5/01 (2006.01); A61F 7/00 (2006.01); A61B 5/053 (2006.01);
U.S. Cl.
CPC ...
A61B 5/6885 (2013.01); A61B 5/036 (2013.01); A61B 5/0422 (2013.01); A61B 5/1107 (2013.01); A61B 5/686 (2013.01); A61B 5/6843 (2013.01); A61B 5/6869 (2013.01); A61B 18/14 (2013.01); A61N 1/0597 (2013.01); A61B 5/0036 (2018.08); A61B 5/0084 (2013.01); A61B 5/01 (2013.01); A61B 5/015 (2013.01); A61B 5/02055 (2013.01); A61B 5/0538 (2013.01); A61B 5/1116 (2013.01); A61B 5/1473 (2013.01); A61B 5/14539 (2013.01); A61B 5/14546 (2013.01); A61B 5/4836 (2013.01); A61B 2018/00351 (2013.01); A61B 2562/028 (2013.01); A61B 2562/0215 (2017.08); A61B 2562/046 (2013.01); A61B 2562/164 (2013.01); A61F 7/007 (2013.01); A61H 23/0245 (2013.01); A61H 2201/10 (2013.01); A61N 1/0563 (2013.01); A61N 1/3621 (2013.01); A61N 1/375 (2013.01); A61N 1/37512 (2017.08); A61N 2/002 (2013.01); A61N 2/006 (2013.01); A61N 5/0603 (2013.01); A61N 5/0622 (2013.01);
Abstract

Provided are devices and methods capable of interfacing with biological tissues, such as organs like the heart, in real-time and using techniques which provide the ability to monitor and control complex physical, chemical, biochemical and thermal properties of the tissues as a function of time. The described devices and methods utilize micro scale sensors and actuators to spatially monitor and control a variety of physical, chemical and biological tissue parameters, such as temperature, pH, spatial position, force, pressure, electrophysiology and to spatially provide a variety of stimuli, such as heat, light, voltage and current.


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