The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 27, 2020

Filed:

Jun. 20, 2017
Applicant:

Metgen Oy, Kaarina, FI;

Inventors:

Klara Birikh, Kaarina, FI;

Anu Minna Maaret Suonpää, Kaarina, FI;

Assignee:

METGEN OY, Kaarina, FI;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/90 (2006.01); C12N 15/00 (2006.01); C12P 19/02 (2006.01); C07H 21/04 (2006.01); C12N 9/92 (2006.01); C12P 19/24 (2006.01); C12N 9/88 (2006.01); C12N 9/96 (2006.01);
U.S. Cl.
CPC ...
C12N 9/92 (2013.01); C12N 9/88 (2013.01); C12N 9/90 (2013.01); C12N 9/96 (2013.01); C12P 19/24 (2013.01); C12Y 402/02002 (2013.01); C12Y 502/01008 (2013.01); C12Y 503/01005 (2013.01); C07K 2319/00 (2013.01);
Abstract

The invention is in the field of biotechnology and involves recombinant DNA technology. It provides means and methods for obtaining an insoluble active fusion protein comprising xylose isomerase activity. More in particular, the invention relates to a method for obtaining active insoluble xylose isomerase, comprising the expression in a host organism of a recombinant gene encoding a fusion protein comprising a xylose isomerase in combination with a PPIase, thereby obtaining the active insoluble xylose isomerase. It also provides recombinant fusion proteins comprising xylose isomerase activity as well as their use in converting xylose to xylulose and glucose to fructose.


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