The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 27, 2020
Filed:
Aug. 25, 2017
Applicant:
Riken, Saitama, JP;
Inventors:
Atsushi Miyawaki, Saitama, JP;
Satoshi Iwano, Saitama, JP;
Assignee:
RIKEN, Saitama, JP;
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 9/02 (2006.01); C12N 15/09 (2006.01); C12Q 1/66 (2006.01);
U.S. Cl.
CPC ...
C12N 9/0069 (2013.01); C12N 15/09 (2013.01); C12Q 1/66 (2013.01); C12Y 113/12005 (2013.01);
Abstract
In order to provide modified luciferase whose substrate specificity to at least one luminescent substrate (e.g., AkaLumine) other than D-luciferin has been improved as compared with to D-luciferin, modified luciferase according to an aspect of the present invention has a mutation at an amino acid corresponding to a 347th amino acid in an amino acid sequence represented by SEQ ID NO: 1.