The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 27, 2020

Filed:

Jan. 12, 2017
Applicant:

Green Cross Holdings Corporation, Yongin-si, Gyeonggi-do, KR;

Inventors:

Jun Sic Kim, Yongin-si, KR;

Hyo Jin Kim, Yongin-si, KR;

Ji Yoon Park, Yongin-si, KR;

Ju Ho Lee, Yongin-si, KR;

Jae Woon Son, Yongin-si, KR;

Yong Won Shin, Yongin-si, KR;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/75 (2006.01); A61K 38/36 (2006.01); B01J 20/08 (2006.01); C07K 1/30 (2006.01); C07K 1/34 (2006.01); C07K 1/36 (2006.01);
U.S. Cl.
CPC ...
C07K 14/75 (2013.01); A61K 38/36 (2013.01); B01J 20/08 (2013.01); C07K 1/30 (2013.01); C07K 1/34 (2013.01); C07K 1/36 (2013.01);
Abstract

A method for purifying fibrinogen includes steps of: (a) precipitating fibrinogen of a fibrinogen-containing solution by adding glycine to the solution for a concentration of glycine to be 1.5 to 2.5M, and then removing a supernatant and recovering a precipitate (1glycine precipitation); (b) dissolving the precipitate of 1glycine precipitation of step (a) in a dissolution buffer to obtain a solution, precipitating the solution by adding glycine thereto for a concentration of glycine to be 0.2 to 1.2M, and recovering a supernatant (2glycine precipitation); (c) precipitating the supernatant of step (b) by adding glycine thereto for a concentration of glycine to be 1.5 to 2.5M, and recovering a precipitate (3glycine precipitation); and (d) dissolving the precipitate of step (c) in a dissolution buffer to obtain a solution, and subjecting the solution to nanofiltration using a nanofilter.


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