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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10815288 B1

PDFFull Text
Expired
Date of Patent:
Oct. 27, 2020

Filed:

Sep. 12, 2013

Antigen-specific helper t-cell receptor genes

Applicant:

International Institute of Cancer Immunology, Inc., Suita-shi, Osaka, JP;

Inventors:

Haruo Sugiyama, Minoo, JP;

Fumihiro Fujiki, Hyogo, JP;

Assignee:

International Institute of Cancer Immunology, Inc., Osaka, JP;

Attorney:

Finnegan, Henderson, Farabow, Garrett & Dunner, LLP

Primary Examiner:

Celine X Qian

Int. Cl.
CPC ...
A61K 48/00 (2006.01); C07K 14/725 (2006.01); C12N 5/0783 (2010.01); A61K 35/17 (2015.01); C12Q 1/6886 (2018.01); C07K 16/28 (2006.01); C12Q 1/6881 (2018.01); G01N 33/569 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/7051 (2013.01); A61K 35/17 (2013.01); C07K 16/28 (2013.01); C12N 5/0636 (2013.01); C12Q 1/6881 (2013.01); C12Q 1/6886 (2013.01); G01N 33/56972 (2013.01); A61K 38/00 (2013.01); C12Q 2600/158 (2013.01); G01N 2333/4703 (2013.01); G01N 2333/70514 (2013.01);
Abstract

The present invention pertains to polynucleotides that encode CDR3 in TCR-[alpha] and TCR-[beta] chain genes of CD4helper T-cells that are specific to WT1 helper peptides having an amino acid sequence represented by SEQ ID NO: 123. The present invention further pertains to the peptides encoded by said polynucleotides. The present invention further pertains to CD4T cells into which TCR genes that contain said polynucleotides have been introduced, the induction of WT1-specific cytotoxic T-lymphocytes (CTLs) using the CD4T-cells, the treatment of cancer, etc.

Find Patent Forward Citations

Sugiyama, Haruo. (2020). Antigen-specific helper t-cell receptor genes (U.S. Patent No. 10815288). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10815288

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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