The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 27, 2020

Filed:

Jan. 09, 2020
Applicant:

Plasma Technologies, Llc, Charleston, SC (US);

Inventors:

Eugene Zurlo, Charleston, SC (US);

Dennis Curtin, Plattsburgh, NY (US);

Peter Radtke, Charleston, SC (US);

Kurt L. Brillhart, Mission Viejo, CA (US);

Assignee:

Plasma Technologies, LLC, Charleston, SC (US);

Attorney:
Int. Cl.
CPC ...
C07K 1/30 (2006.01); G01N 33/49 (2006.01); G01N 30/12 (2006.01); G01N 1/40 (2006.01); C07K 1/36 (2006.01); G01N 30/06 (2006.01); C07K 1/34 (2006.01); C07K 1/18 (2006.01); B01D 15/36 (2006.01); B01D 15/38 (2006.01);
U.S. Cl.
CPC ...
C07K 1/30 (2013.01); C07K 1/303 (2013.01); C07K 1/34 (2013.01); C07K 1/36 (2013.01); G01N 1/40 (2013.01); G01N 1/4055 (2013.01); G01N 30/06 (2013.01); G01N 30/12 (2013.01); G01N 33/491 (2013.01); B01D 15/361 (2013.01); B01D 15/38 (2013.01); C07K 1/18 (2013.01);
Abstract

Methods for isolating proteins from solution by precipitation are provided. A nonvolatile precipitation agent is added to an aqueous protein solution at a low concentration. Water is then removed from the resulting solution until the precipitant and the protein content of the solution increase to a concentration that provides the desired segregation of proteins between supernatant and precipitate. Additional water can be removed from the supernatant to provide additional fractionation. Water can be removed by evaporation (e.g. under reduced pressure) and/or diafiltration.


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