The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 27, 2020
Filed:
Dec. 19, 2019
Ono Pharmaceutical Co., Ltd., Osaka, JP;
Motoyuki Tanaka, Osaka, JP;
Takashi Kondo, Osaka, JP;
Yasuo Hirooka, Osaka, JP;
Taihei Nishiyama, Osaka, JP;
Atsushi Hiramatsu, Osaka, JP;
Tomoyuki Koda, Osaka, JP;
Sho Kouyama, Osaka, JP;
ONO PHARMACEUTICAL CO., LTD., Osaka, JP;
Abstract
A compound represented by general formula (I) (wherein all symbols are as defined in the description) or a salt, solvate, N-oxide form or prodrug thereof is a potent FXIa inhibitor, has excellent oral absorption properties and kinetics in blood, can exert a potent anti-coagulation activity over a long period of time after being administered orally, and has a discrepancy between the anti-coagulation activity thereof and the CYP-inhibiting activity thereof. Therefore, the compound or the salt, solvate, N-oxide form or prodrug thereof can be used as an efficient prophylactic and/or therapeutic agent for vascular occlusive diseases.